Review Article

Genetics Of Alcohol Use Disorder

Kaya Hasan,Kaya Özlem Bolat,Dilbaz Nesrin
2017, 1(1), s:33-46

Introduction: Alcohol Use Disorder (AUD) is a chronic
psychiatric disorder characterizes by harmful drinking
patterns leading to negative emotional, physical, and
social outcomes. Twin, family, and adoption studies
have consistently demonstrated that genetic factors
play a critical role in the pathogenesis of AUD. Various
studies have aimed to identify genes that contribute
to susceptibility to AUD. In this paper, we provide
an review of genetic studies on AUD, including twin
studies, linkage studies, candidate gene studies, and
genome-wide association studies (GWAS). Growing
evidence indicates that AUD is a complex genetic
disease, with variations in a substantial number of gene
affecting a person’s risk of AUD. Some of these genes
have been identified, including two genes involved in the
metabolism of ethanol (ADH1B and ALDH2) that have
the strongest known affects on the risk of AUD. Studies
continue to find out other genes in which variants affect
the risk of AUD or related traits, including GABRA2,
DRD2, OPRM1, MAOA and PECR. As more variants
are analysed and studies are integrated for meta-analysis
to obtain increased sample sizes, an enhanced picture of
the many genes and pathways that affect the risk of AUD
will be possible.

Original Article

Treatment And Approaches On Acute Agitation Among in Patients in a Private Psychıatry Hospital

Darçın Aslı Enez,Noyan Cemal Onur,Nurmedov Serdar,Kaya Hasan,Dilbaz Nesrin
2017, 1(1), s:26-32

Aim: It is aimed to determine the association between
the indications of acute agitation call, applied
treatment, applied restraint and seclusion with the
sociodemographical and clinical characteristics of
Method: Among inpatients in a private psychiatry
hospital, medical records of whom has a form filled for
acute agitation between June 2013-April 2014 examined
retrospectively, 137 medical records enrolled. Acute
intervation form and brief psychiatric rating scale points
that had been filled in the same day were determined.
Results: In the duration of the study acute agitation call
applied for 16.4% of inpatients, 1.9% were restrained,
8% were secluded and 9.4% were given acute medication.
While the applied physical restraint and seclusion rates
did not differ during the day, drug applications were
found in higher rates during daytime hours (p<0.05).
According to the hours of application, the duration of
physical restraints were constant throughout the day
while the duration of seclusions were longer in the
night hours (p<0.05). The most common causes of
acute agitation were aggression, threat of violence and
treatment rejection. There was no difference approaches
to acute agitation in terms of the diagnosis. The majority
of selected drug treatments for acute agitation were
intramuscular injections. No association was found
between scale scores and the duration of any application.
Conclusion: Lower rates of restraints in our study could
be associated with that the sample of this study was
chosen from a private psychiatry hospital. There is need
for further training among treatment team and studies in
this area to shed light on the development of approaches.

Original Article

Validity and Reliability of the Turkish Version of the Bergen Facebook Addiction Scale among University Students

Ülke Zeynep,Noyan Cemal Onur,Dilbaz Nesrin
2017, 1(1), s:16-25

Objective: The objective of this study was to adapt the
“Bergen Facebook Addiction Scale (BFAS)” developed
by Adreassen et al (1) into Turkish, and to evaluate
the reliability and validity of the Turkish version of the
Bergen Facebook Addiction among university students.
Method: The study was conducted in 2015 at Uskudar
University and Yeditepe University (Istanbul-Turkey)
with a total of 300 students from different majors and
age groups. The draft scale was finalized after being
translated and corrected by experts in the relevant fields.
To determine the validity of the scale; factor analysis was
performed and the results revealed that, of the 6 items
reflecting the six core elements. It was detected that all
items were distinctive with respect to relationship of
each item with its related factor. Reliability level was
determined by test – retest and internal consistency
analysis. In addition, to test the criterion dependence
validity of the scale, the correlation between the data
gathered from Bergen Facebook Addiction Scale was
analyzed respectively with data collected from the Smart
Phone Addiction Scale, Facebook Use Variance and
Facebook Addiction Self-evaluation.
Results: The internal consistency coefficient was
calculated using the Cronbach’s Alpha formula and
gave a result of crα= .89. The 3-week test-retest validity
Cronbach’s alpha was .76 for the six-item Bergen
Facebook Addiction Scale. The factor analysis and testretest
results confirmed the reliability and validity of the
6-item scale.
Conclusion: Bergen Facebook Addiction Scale is able
to measure reliably, and the scale is a valid and reliable
tool to be employed in a clinical environment to predict
addiction levels of individuals regarding Facebook use in
the Turkish society as well.


Çelik Hüseyin
2017, 1(1), s:13-15

DOI : 0


Dilbaz Nesrin
2017, 1(1), s:9-11

DOI : 0

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ISSN (Print) 2548-0715
ISSN (Online)