Kleptomania is a clinical condition in which the desire to steal different objects cannot be inhibited regardless of value. It is classified as “impulse control disorder” in DSM 5. A 24-year-old patient with alcohol use disorder developed kleptomania after successful treatment. In this case, kleptomania can also be evaluated from the perspective of addiction.

Substance Use Disorder is an major public health problem that is difficult to treat with devastating effects on the patients and relatives. The main difficulties in treatment process is the termination of oral medical treatment of the patient with poor compliance and the relapse of substance use with increased craving. New alternatives to oral therapy have been developed to treat addiction disease. Subcutaneous Naltrexone pellet is one of the current treatment options in the treatment of alcohol and opioid addiction. Pain, vomiting, dehydration, wound infection and hematoma, itching, local tissue reaction are common side effects reported with naltrexone implants. In this study, two cases of soft tissue infection following naltrexone implant application will be discussed. We think that our study will contribute to the literature regarding the management of complications that may develop due to Naltrexone implants. Keywords:

The association of alcohol /substance use disorder and attention deficit hyperactivity disorder (ADHD) is a frequently reported condition. The comorbidity of these two diseases both compromises treatment compliance and increases mortality and morbidity rates. The medical treatments used in ADHD treatment are also very limited due to their potential for abuse. In this case report, the regression of attention deficit symptoms and improvement in the neuropsychometric tests due to atomoxetine treatment in opiate use disorder patient will be presented.

Pathological gambling is defined as persistent and repetitive gambling behaviors, characterized by the inability to control the gambling behavior of the individual, family or professional functionality. It is stated that the possibility of occurrence of alcohol and substance use disorders is increased after obesity operations, which have been frequently applied in recent years. Until now, gambling disorder, which is considered as impulse control disorder, is evaluated under the category of addiction behaviors with DSM-5. In this case report, the case of gambling disorder following bariatric surgery will be discussed.

Buprenorphine is a semi-synthetic opioid derived from thebaine. It is used for analgesic effect and opioid substitution therapy. In Turkey, buprenorphine and naloxone combination (Suboxone®) has been used in opioid substitution therapy since 2010. In this paper respiratory depression arising after buprenorphine use together with benzodiazepine will be told and possible mechanisms of this interaction will be discussed.

Psychoactive substance use disorder can be defined as a chronic illness with an uncontrollable impulsivity to drug use by affecting reward, motivation, memory and decision making mechanisms in individuals brains. These substances can cause dangerous consequences in the lives of individuals by causing addiction and, on the other hand, by stimulating or depressing the central nervous system, causing mood, mental state, behavioral and motor function disorders. Caffeine, hallucinogens, lysergic acid diethylamide (LSD), inhalants, nicotine, phencyclidine, sedatives, hypnotics, anxiolytics, anabolic steroids, nitrous oxide are among the addictive substances (1 ,2). The incidence of psychiatric disorders in patients with substance use disorders is 2.7 times higher. It has been reported that 70-75% of individuals with substance use disorders are accompanied by at least one psychiatric disorder (2,3). It is also known that substance abuse is more common in psychiatric disorders. In a study conducted in Turkey psychoactive substance use in schizophrenia 3.2%, while bipolar disorder is reported to be 3.5%. In the same study, 39% of the patients who received substance abuse and inpatient treatment received psychotic disorder and 23% received bipolar disorder (4).

Very common psychotic disorder or comorbid condition among substance use related disorders is clinically important. One of the biggest challenges faced by clinicians in this case is the primary-secondary distinction (5). In this study, psychoactive substance use and psychosis association and primary-secondary distinction are discussed through two case studies.

Naltrexone subcutaneous implants are among the new alternatives in the treatment of alcohol and opioid addictions in our country.Nausea, vomitting, headache, skin rash, depression, anxiety and loss of energy are side effects reported in the use of naltrexone. This paper discusses a case of itching and skin eruptions following the application of naltrexone subcutaneous implant.

Pethidine(Meperidine) is a synthetic opioid analgesic of the phenylpiperidine class. Since 1940ies, addictive potential of pethidine was documented in many reports. Pethidine addiction is also common among medical doctors and nurses. We present clinical features and treatment response of a married couple, a gastroenterologist and a nurse who were admitted  with  pethidine addiction. A 34-year-old male(a gastroenterologist) and a 26-year-old female(a nurse) married couple were admitted to clinic with the use of pethidine intravenously. While male patient refused treatment, female patient continued her treatment in inpatient service. Healthcare professionals have to be cautious while using and prescribing drugs with addiction potential. Surgeons, anesthesiologists, gastroenterologists psychiatrists and surgical nurses are the risk groups for dependency among those professionals.